CSE1L / Biotin / 3D8
CSE1L / Biotin / 3D8
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | 244982-Biotin-100UL (View supplier product page) | |
| Size | 100 μl | |
| Price | $681.00 | |
| Antigen | CSE1L | |
| Clone | 3D8 | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | Biotin | |
| Target Species | Human | |
| Applications | ELISA, IF, IHC, WB | |
| Description | CSE1L (CSE1 Chromosome Segregation 1-like (yeast), CAS, CSE1, MGC117283, MGC130036, MGC130037, XPO2) (Biotin) Mab 3D8 |
About CSE1L and Biotin
| CSE1L | Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012] |
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Citations
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