C-Myc / MaxLight 650 / 0.N.222, 9E10.3
C-Myc / MaxLight 650 / 0.N.222, 9E10.3
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | C0035-10X-ML650-100UL (View supplier product page) | |
| Size | 100 μl | |
| Price | $864.00 | |
| Antigen | C-Myc | |
| Clone | 0.N.222, 9E10.3 | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | MaxLight 650 | |
| Target Species | Human | |
| Applications | IF, IHC, IP, WB | |
| Description | c-myc (Myc, myc-1, Cellular myelocytomatosis oncogene, Myc2, Niard, Nird, Transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog) (BSA & Azide Free) (MaxLight 650) Mab 0.N.222, 9E10.3 |
About C-Myc and MaxLight 650
| C-Myc | This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017] | |
|---|---|---|
| MaxLight 650 | MaxLight 650 is excited by the 640 laser and emission captured by the 670/30 filter. It can be used with the following analysis platforms: Labeling, Flow Cytometry, Fluorescence Microscopy, Fluorescence Microscopy. |
Citations
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