CD43 / MaxLight 750 / 1B11

Product Details
Supplier US Biological
Catalog #: C2397-76R-ML750-100UL (View supplier product page)
Size 100 μl
Price $666.00
Antigen CD43
Clone 1B11
Host Rat
Isotype IgG2a
Conjugate MaxLight 750
Target Species Mouse
Applications IHC, IP, WB
Description CD43 (CD43 Antigen, Galactoglycoprotein, GALGP, GPL115, Leukocyte Sialoglycoprotein, Leukosialin, LSN, Sialophorin, SPN) (MaxLight 750) Mab 1B11
About CD43 and MaxLight 750
CD43 This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]
MaxLight 750 MaxLight 750 is excited by the laser and emission captured by the 780/60 filter. It can be used with the following analysis platforms: Labeling, Flow Cytometry, Fluorescence Microscopy, Fluorescence Microscopy.
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MaxLight 750 Excitation and Emission Spectra