CD207 / MaxLight 405 /
CD207 / MaxLight 405 /
Product Details
Supplier | US Biological | |
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Catalog #: | 124574-ML405-100UL (View supplier product page) | |
Size | 100 μl | |
Price | $718.00 | |
Antigen | CD207 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | MaxLight 405 | |
Target Species | Human | |
Applications | WB | |
Description | CD207 (C-type Lectin Domain Family 4 Member K, Langerin, CLEC4K) (MaxLight 405) Pab |
About CD207 and MaxLight 405
CD207 | The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. [provided by RefSeq, Aug 2010] | |
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MaxLight 405 | MaxLight 405 is excited by the 405 laser and emission captured by the 450/50 filter. It can be used with the following analysis platforms: Labeling, Flow Cytometry, Fluorescence Microscopy, Fluorescence Microscopy. |