CD134 / Biotin / OX-40
CD134 / Biotin / OX-40
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | C2515-16H-Biotin-100UL (View supplier product page) | |
| Size | 100 μl | |
| Price | $666.00 | |
| Antigen | CD134 | |
| Clone | OX-40 | |
| Host | Mouse | |
| Isotype | IgG2b | |
| Conjugate | Biotin | |
| Target Species | Rat | |
| Applications | IHC, IP | |
| Description | CD134 (CD134 Antigen, ACT35, ACT35 Antigen, Lymphoid Activation Antigen ACT35, OX40, OX40 Cell Surface Antigen, OX40 Homolog, OX40L Receptor, RP5-902P8.3, TAX Transcriptionally-activated Glycoprotein 1 Receptor, Tumor Necrosis Factor Receptor Superfamily Member 4, TNFRSF4, Txgp1L) (Biotin) Mab OX-40 |
About CD134 and Biotin
| CD134 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008] |
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Citations
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