CD11b / HRP / ED7
CD11b / HRP / ED7
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | C2262-35E-HRP-100UL (View supplier product page) | |
| Size | 100 μl | |
| Price | $788.00 | |
| Antigen | CD11b | |
| Clone | ED7 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | HRP | |
| Target Species | Rat | |
| Applications | IHC | |
| Description | CD11b (Cell Surface Glycoprotein MAC1 Alpha Subunit, Complement Component Receptor 3 Alpha, CR3A, ITGAM, MAC1A, MO1A, Neutrophil Adherence Receptor) (HRP) Mab ED7 |
About CD11b and HRP
| CD11b | This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] |
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Citations
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