FluoroFinder

	Supplier	US Biological
	Catalog #:	124501-PE-100UL (View supplier product page)
	Size	100 μl
	Price	$681.00
	Antigen	CCT5
	Clone	4E5-4B1
	Host	Mouse
	Isotype	IgG1 κ
	Conjugate	PE
	Target Species	Human
	Applications	ELISA, IF, IHC, WB
	Description	CCT5 (T-complex Protein 1 Subunit epsilon, TCP-1-epsilon, CCT-epsilon, KIAA0098, CCTE) (PE) Mab 4E5-4B1

	CCT5	The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015]
	PE	Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.

	Additional Sources

CCT5 / PE / 4E5-4B1