Caspase 9 / Biotin /

Product Details
Supplier US Biological
Catalog #: 214561-Biotin-100UL (View supplier product page)
Size 100 μl
Price $736.00
Antigen Caspase 9
Clone
Host Rabbit
Isotype IgG
Conjugate Biotin
Target Species Human
Applications WB
Description Caspase-9 (ICE-LAP6, McL6, Apaf-3) (Biotin) Pab
About Caspase 9 and Biotin
Caspase 9 This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Citations
Additional
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Reviews & Ratings
Biotin Excitation and Emission Spectra