Caspase 3 / MaxLight 750 / 4D3

Product Details
Supplier US Biological
Catalog #: 124362-ML750-100UL (View supplier product page)
Size 100 μl
Price $681.00
Antigen Caspase 3
Clone 4D3
Host Mouse
Isotype IgG2a κ
Conjugate MaxLight 750
Target Species Human
Applications FC
Description Caspase 3 (Caspase-3, CASP3, CASP-3, Apopain, Cysteine Protease CPP32, CPP32, CPP-32, CPP32B, Protein Yama, SREBP Cleavage Activity 1, SCA-1) (MaxLight 750) Mab 4D3
About Caspase 3 and MaxLight 750
Caspase 3 The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. [provided by RefSeq, Aug 2017]
MaxLight 750 MaxLight 750 is excited by the laser and emission captured by the 780/60 filter. It can be used with the following analysis platforms: Labeling, Flow Cytometry, Fluorescence Microscopy, Fluorescence Microscopy.
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MaxLight 750 Excitation and Emission Spectra