Cadherin-12 / Biotin /
Cadherin-12 / Biotin /
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | 308714-50UG (View supplier product page) | |
| Size | 50 μg | |
| Price | $365.00 | |
| Antigen | Cadherin-12 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Biotin | |
| Target Species | Human | |
| Applications | ELISA, IHC, WB | |
| Description | Cadherin-12 (Biotin) Pab | | |
About Cadherin-12 and Biotin
| Cadherin-12 | This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis. [provided by RefSeq, Nov 2015] |
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Citations
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