FluoroFinder

	Supplier	US Biological
	Catalog #:	032579-FITC-200UL (View supplier product page)
	Size	200 μl
	Price	$711.00
	Antigen	BRF1
	Clone
	Host	Rabbit
	Isotype	IgG
	Conjugate	FITC
	Target Species	Human
	Applications	ELISA, WB
	Description	BRF1, ID (BRF1, BRF, GTF3B, TAF3B2, TAF3C, Transcription factor IIIB 90kD subunit, B-related factor 1, TATA box-binding protein-associated factor, RNA polymerase III, subunit 2) (FITC) Pab

	BRF1	This gene encodes one of the three subunits of the RNA polymerase III transcription factor complex. This complex plays a central role in transcription initiation by RNA polymerase III on genes encoding tRNA, 5S rRNA, and other small structural RNAs. The gene product belongs to the TF2B family. Several alternatively spliced variants encoding different isoforms, that function at different promoters transcribed by RNA polymerase III, have been identified. [provided by RefSeq, Jun 2011]
	FITC	Fluorescein isothiocyanate (FITC) has an excitation peak at 495 nm and an emission peak at 519 nm. The name FITC is a misnomer in that the isothiocyanate is a reactive form of this dye. Once FITC is conjugated to an antibody, it is simply Fluorescein conjugated. FITC is one of the most widely used dyes for fluorescent applications, therefore most instruments come standard with a 488 nm laser and FITC filter set up. FITC is commonly conjugated to secondary antibodies and used in applications such as flow cytometry, immunocytochemistry, and immunohistochemistry. FITC is relatively dim, sensitive to photobleaching and it is susceptible to changes is pH. There are better performing alternatives to FITC, like Vio®Bright 515, Alexa Fluor™ 488, iFluor® 488, CF®488A and DY-488. FITC is a long-time generic dye with no sole manufacturer or trademark.

	Additional Sources

BRF1 / FITC /