BRAF / Biotin / 4F4
BRAF / Biotin / 4F4
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | 243875-Biotin-100UL (View supplier product page) | |
| Size | 100 μl | |
| Price | $681.00 | |
| Antigen | BRAF | |
| Clone | 4F4 | |
| Host | Mouse | |
| Isotype | IgG2a κ | |
| Conjugate | Biotin | |
| Target Species | Human | |
| Applications | ELISA, WB | |
| Description | BRAF (v-raf murine Sarcoma Viral Oncogene Homolog B1, B-RAF1, BRAF1, FLJ95109, MGC126806, MGC138284, RAFB1) (Biotin) Mab 4F4 |
About BRAF and Biotin
| BRAF | This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome. [provided by RefSeq, Aug 2017] |
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Citations
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