B1 Bradykinin Receptor / PE /
B1 Bradykinin Receptor / PE /
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | 123914-PE-100UL (View supplier product page) | |
| Size | 100 μl | |
| Price | $718.00 | |
| Antigen | B1 Bradykinin Receptor | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | PE | |
| Target Species | Human | |
| Applications | WB | |
| Description | BDKRB1 (B1 Bradykinin Receptor, BK-1 Receptor, B1R, BRADYB1) (PE) Pab |
About B1 Bradykinin Receptor and PE
| B1 Bradykinin Receptor | Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. The protein encoded by this gene belongs to the G-protein coupled receptor 1 family. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. [provided by RefSeq, Aug 2020] | |
|---|---|---|
| PE | Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts. |
Citations
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