RUBCN / Biotin /
RUBCN / Biotin /
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | 032427-Biotin-200UL (View supplier product page) | |
| Size | 200 μl | |
| Price | $711.00 | |
| Antigen | RUBCN | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Biotin | |
| Target Species | Human | |
| Applications | ELISA, IHC, WB | |
| Description | BARON, NT (KIAA0226, Run domain Beclin-1 interacting and cystein-rich containing protein, Beclin-1 associated RUN domain containing protein) (Biotin) Pab |
About RUBCN and Biotin
| RUBCN | The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014] |
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Citations
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