ATR / PE / 1000000000

Product Details
Supplier US Biological
Catalog #: 243654-PE-100UL (View supplier product page)
Size 100 μl
Price $681.00
Antigen ATR
Clone 1000000000
Host Mouse
Isotype IgG1 κ
Conjugate PE
Target Species Human
Applications ELISA, IHC
Description ATR (ataxia Telangiectasia and Rad3 Related, FRP1, MEC1, SCKL, SCKL1) (PE) Mab 1.0e+9
About ATR and PE
ATR The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. [provided by RefSeq, Aug 2017]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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PE Excitation and Emission Spectra