FluoroFinder

	Supplier	US Biological
	Catalog #:	243652-PE-100UL (View supplier product page)
	Size	100 μl
	Price	$681.00
	Antigen	ATP7b
	Clone	3A12
	Host	Mouse
	Isotype	IgG1 κ
	Conjugate	PE
	Target Species	Human
	Applications	ELISA, WB
	Description	ATP7B (ATPase, Cu++ Transporting, beta Polypeptide, PWD, WC1, WD, WND) (PE) Mab 3A12

	ATP7b	This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein is a monomer, and functions as a copper-transporting ATPase which exports copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease which is characterized by copper accumulation. [provided by RefSeq, Dec 2019]
	PE	Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.

	Additional Sources

ATP7b / PE / 3A12