Arrestin beta 2 / APC /
Arrestin beta 2 / APC /
Product Details
Supplier | US Biological | |
---|---|---|
Catalog #: | 209613-APC-100UL (View supplier product page) | |
Size | 100 μl | |
Price | $865.00 | |
Antigen | Arrestin beta 2 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | APC | |
Target Species | Human | |
Applications | IF, IHC, WB | |
Description | ARRB2 (Arrestin beta-2, Beta-arrestin-2, ARB2, ARR2, BARR2) (APC) Pab |
About Arrestin beta 2 and APC
Arrestin beta 2 | Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012] | |
---|---|---|
APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |