Arrestin beta 2 / APC /

Product Details
Supplier US Biological
Catalog #: 209613-APC-100UL (View supplier product page)
Size 100 μl
Price $865.00
Antigen Arrestin beta 2
Clone
Host Rabbit
Isotype IgG
Conjugate APC
Target Species Human
Applications IF, IHC, WB
Description ARRB2 (Arrestin beta-2, Beta-arrestin-2, ARB2, ARR2, BARR2) (APC) Pab
About Arrestin beta 2 and APC
Arrestin beta 2 Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]
APC Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
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APC Excitation and Emission Spectra