APC / MaxLight 550 / 13H8
APC / MaxLight 550 / 13H8
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | 137553-ML550-100UL (View supplier product page) | |
| Size | 100 μl | |
| Price | $761.00 | |
| Antigen | APC | |
| Clone | 13H8 | |
| Host | Rat | |
| Isotype | IgG2a | |
| Conjugate | MaxLight 550 | |
| Target Species | Mouse | |
| Applications | IF, WB | |
| Description | APC (Adenomatous Polyposis Coli Protein, Protein APC, mAPC) (MaxLight 550) Mab 13H8 |
About APC and MaxLight 550
| APC | This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Mutations in the APC gene have been found to occur in most colorectal cancers. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Dec 2019] | |
|---|---|---|
| MaxLight 550 | MaxLight 550 is excited by the 561 laser and emission captured by the 585/42 filter. It can be used with the following analysis platforms: Labeling, Flow Cytometry, Fluorescence Microscopy, Fluorescence Microscopy. |
Citations
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