ANTXR1 / MaxLight 650 /
ANTXR1 / MaxLight 650 /
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | A2296-97D-ML650-100UL (View supplier product page) | |
| Size | 100 μl | |
| Price | $711.00 | |
| Antigen | ANTXR1 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | MaxLight 650 | |
| Target Species | Human | |
| Applications | FC, IHC, WB | |
| Description | ANTXR1 (Y382) (Anthrax Toxin Receptor 1, Tumor Endothelial Marker 8, ATR, TEM8) (MaxLight 650) Pab |
About ANTXR1 and MaxLight 650
| ANTXR1 | This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008] | |
|---|---|---|
| MaxLight 650 | MaxLight 650 is excited by the 640 laser and emission captured by the 670/30 filter. It can be used with the following analysis platforms: Labeling, Flow Cytometry, Fluorescence Microscopy, Fluorescence Microscopy. |
Citations
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