FluoroFinder

	Supplier	US Biological
	Catalog #:	A2295-17-APC-100UL (View supplier product page)
	Size	100 μl
	Price	$789.00
	Antigen	Ankyrin B
	Clone	3G7
	Host	Mouse
	Isotype	IgG1
	Conjugate	APC
	Target Species	Human
	Applications	ELISA, WB
	Description	Ankyrin B (RFXANK, Regulatory Factor X) (APC) Mab 3G7

	Ankyrin B	This gene encodes a member of the ankyrin family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton. Ankyrins play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. The protein encoded by this gene is required for targeting and stability of Na/Ca exchanger 1 in cardiomyocytes. Mutations in this gene cause long QT syndrome 4 and cardiac arrhythmia syndrome. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq, Dec 2011]
	APC	Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.

	Additional Sources

Ankyrin B / APC / 3G7