Adenylosuccinate Lyase / Biotin /
Adenylosuccinate Lyase / Biotin /
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | 218801-Biotin-100UL (View supplier product page) | |
| Size | 100 μl | |
| Price | $865.00 | |
| Antigen | Adenylosuccinate Lyase | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Biotin | |
| Target Species | Human | |
| Applications | IHC, WB | |
| Description | ADSL (ASL, AMPS, ASASE, Adenylosuccinate Lyase) (Biotin) Pab |
About Adenylosuccinate Lyase and Biotin
| Adenylosuccinate Lyase | The protein encoded by this gene belongs to the lyase 1 family. It is an essential enzyme involved in purine metabolism, and catalyzes two non-sequential reactions in the de novo purine biosynthetic pathway: the conversion of succinylaminoimidazole carboxamide ribotide (SAICAR) to aminoimidazole carboxamide ribotide (AICAR) and the conversion of adenylosuccinate (S-AMP) to adenosine monophosphate (AMP). Mutations in this gene are associated with adenylosuccinase deficiency (ADSLD), a disorder marked with psychomotor retardation, epilepsy or autistic features. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015] |
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Citations
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