Adenylosuccinate Lyase / HRP /
Adenylosuccinate Lyase / HRP /
Product Details
Supplier | US Biological | |
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Catalog #: | 123034-HRP-100UL (View supplier product page) | |
Size | 100 μl | |
Price | $718.00 | |
Antigen | Adenylosuccinate Lyase | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | HRP | |
Target Species | Human | |
Applications | WB | |
Description | ADSL (Adenylosuccinate Lyase, Adenylosuccinase, ASase, ASL, AMPS) (HRP) Pab |
About Adenylosuccinate Lyase and HRP
Adenylosuccinate Lyase | The protein encoded by this gene belongs to the lyase 1 family. It is an essential enzyme involved in purine metabolism, and catalyzes two non-sequential reactions in the de novo purine biosynthetic pathway: the conversion of succinylaminoimidazole carboxamide ribotide (SAICAR) to aminoimidazole carboxamide ribotide (AICAR) and the conversion of adenylosuccinate (S-AMP) to adenosine monophosphate (AMP). Mutations in this gene are associated with adenylosuccinase deficiency (ADSLD), a disorder marked with psychomotor retardation, epilepsy or autistic features. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015] |
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