ABCG2 / APC / 9H68
ABCG2 / APC / 9H68
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | B0808-09-100TESTS (View supplier product page) | |
| Size | 100 Tests | |
| Price | $848.00 | |
| Antigen | ABCG2 | |
| Clone | 9H68 | |
| Host | Mouse | |
| Isotype | IgG2b | |
| Conjugate | APC | |
| Target Species | Human | |
| Applications | FC | |
| Description | Bcrp1 (ABCG2) (APC) Mab 9H68 |
About ABCG2 and APC
| ABCG2 | The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] | |
|---|---|---|
| APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |
Citations
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