ABCG2 / HRP / 1G1
ABCG2 / HRP / 1G1
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | 122820-HRP-100UL (View supplier product page) | |
| Size | 100 μl | |
| Price | $681.00 | |
| Antigen | ABCG2 | |
| Clone | 1G1 | |
| Host | Mouse | |
| Isotype | IgG2a κ | |
| Conjugate | HRP | |
| Target Species | Human | |
| Applications | ELISA, WB | |
| Description | ABCG2 (ATP-binding Cassette Sub-family G Member 2, Placenta-specific ATP-binding Cassette Transporter, Breast Cancer Resistance Protein, Mitoxantrone Resistance-associated Protein, CD338 Antigen, CDw338, ABCP, BCRP, BCRP1, MXR) (HRP) Mab 1G1 |
About ABCG2 and HRP
| ABCG2 | The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] |
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Citations
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