ABCA1 / APC / 5A1-1422
ABCA1 / APC / 5A1-1422
Product Details
Supplier | US Biological | |
---|---|---|
Catalog #: | A0004-01A-APC-100UL (View supplier product page) | |
Size | 100 μl | |
Price | $788.00 | |
Antigen | ABCA1 | |
Clone | 5A1-1422 | |
Host | Rat | |
Isotype | IgG2a | |
Conjugate | APC | |
Target Species | Mouse | |
Applications | ||
Description | ABCA1 (ABC 1, ABC Transporter 1, ATP-binding Cassette 1, ATP-binding Cassette Transporter 1, CERP, Cholesterol Efflux Regulatory Protein, HDLDT1, TGD) (APC) Mab 5A1-1422 |
About ABCA1 and APC
ABCA1 | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency. [provided by RefSeq, Sep 2019] | |
---|---|---|
APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |