ZAP70 / HRP /

Product Details
Supplier Applied Biological Materials (ABM)
Catalog #: Y056707-100UL (View supplier product page)
Size 100 μl
Price $386.00
Antigen ZAP70
Clone
Host Mouse
Isotype IgG1
Conjugate HRP
Target Species Human
Applications ELISA
Description Anti-Mouse Anti-Human ZAP-70 (TCR )-HRP Conjugate Antibody
About ZAP70 and HRP
ZAP70 This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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HRP Excitation and Emission Spectra