Estrogen Receptor alpha / Cy5 /

Product Details
Supplier Bioss
Catalog #: bs-0254R-Cy5 (View supplier product page)
Size 100 μl
Price $468.00
Antigen Estrogen Receptor alpha
Clone
Host Rabbit
Isotype IgG
Conjugate Cy5
Target Species Human, Mouse
Applications FC
Description ER-Alpha Polyclonal Antibody, Cy5 Conjugated
About Estrogen Receptor alpha and Cy5
Estrogen Receptor alpha This gene encodes an estrogen receptor and ligand-activated transcription factor. The canonical protein contains an N-terminal ligand-independent transactivation domain, a central DNA binding domain, a hinge domain, and a C-terminal ligand-dependent transactivation domain. The protein localizes to the nucleus where it may form either a homodimer or a heterodimer with estrogen receptor 2. The protein encoded by this gene regulates the transcription of many estrogen-inducible genes that play a role in growth, metabolism, sexual development, gestation, and other reproductive functions and is expressed in many non-reproductive tissues. The receptor encoded by this gene plays a key role in breast cancer, endometrial cancer, and osteoporosis. This gene is reported to have dozens of transcript variants due to the use of alternate promoters and alternative splicing, however, the full-length nature of many of these variants remain uncertain. [provided by RefSeq, Jul 2020]
Cy5 Cy5 is an important historical fluorophore from GE Healthcare. It has an excitation peak at 649 nm and an emission peak at 667 nm. Spectrally its similar to Alexa Fluor™ 647.
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Reviews & Ratings
Cy5 Excitation and Emission Spectra