Sox9 / Unconjugated / SOX9/2398

Product Details
Supplier NSJ Bioreagents
Catalog #: V7459SAF-100UG (View supplier product page)
Size 100 μg
Price $554.00
Antigen Sox9
Clone SOX9/2398
Host Mouse
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications IHC-P
Description Sox genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. SOX9 plays an important role in the normal skeletal development. It may regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes.
About Sox9 and Purified
Sox9 The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra