Pan Cytokeratin / Unconjugated / KRTL/1077, KRTH/1076

Product Details
Supplier NSJ Bioreagents
Catalog #: V3051-100UG (View supplier product page)
Size 100 μg
Price $554.00
Antigen Pan Cytokeratin
Clone KRTL/1077, KRTH/1076
Host Mouse
Isotype IgG
Conjugate Unconjugated
Target Species Human, Rat
Applications IHC-P
Description Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which include Keratins 1, 3, 4, 5, 6, 8, 10, 14, 15, 16, and 19. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. KRTL/KRTH is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas.
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Purified Excitation and Emission Spectra