MART-1 / Unconjugated / SPM555

Product Details
Supplier NSJ Bioreagents
Catalog #: V9125SAF-100UG (View supplier product page)
Size 100 μg
Price $554.00
Antigen MART-1
Clone SPM555
Host Mouse
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications IHC-P, WB
Description This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1/Melan-A is present in melanosomes and endoplasmic reticulum. This mAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
About MART-1 and Purified
MART-1 Located in endoplasmic reticulum membrane; melanosome; and trans-Golgi network. [provided by Alliance of Genome Resources, Apr 2022]
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Reviews & Ratings
Purified Excitation and Emission Spectra