Lambda Light Chain / Unconjugated / HP6054

Product Details
Supplier NSJ Bioreagents
Catalog #: V3151-100UG (View supplier product page)
Size 100 μg
Price $554.00
Antigen Lambda Light Chain
Clone HP6054
Host Mouse
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications FC, IF, WB, IHC-P
Description This mAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with kappa light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
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Purified Excitation and Emission Spectra