CD30 / Unconjugated / CDLA30-2R

Product Details
Supplier NSJ Bioreagents
Catalog #: V3707-100UG (View supplier product page)
Size 100 μg
Price $554.00
Antigen CD30
Clone CDLA30-2R
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications IHC-P
Description CD30 is the receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B. [UniProt]
About CD30 and Purified
CD30 The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra