NSD2 / Unconjugated /

Product Details
Supplier Biorbyt
Catalog #: orb67150 (View supplier product page)
Size 100 ul
Price $656.20
Antigen NSD2
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications WB
Description Rabbit polyclonal to WHSC1.Wolf-Hirschhorn syndrome candidate 1 protein (WHSC1) is a probable histone methyltransferasewhich may act as a transcription regulator that binds DNA and suppresses IL5 transcription. WHSC1contains four domains present in other developmental proteins: a PWWP domain, an HMG box, aSET domain and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion ofthe distal short arm of chromosome 4. The WHSC1 gene maps to the 165 kb WHS critical region andhas also been implicated in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas.Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
About NSD2 and Purified
NSD2 This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra