Siglec-8 / Biotin /

Product Details
Supplier Biorbyt
Catalog #: orb724913 (View supplier product page)
Size 100 ul
Price $598.40
Antigen Siglec-8
Clone
Host Rabbit
Isotype IgG
Conjugate Biotin
Target Species Human
Applications
Description Rabbit polyclonal antibody against SIGLEC8 conjugated to Biotin
About Siglec-8 and Biotin
Siglec-8 Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).[supplied by OMIM, May 2010]
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Biotin Excitation and Emission Spectra