PTPN12 / HRP /

Product Details
Supplier Biorbyt
Catalog #: orb473742 (View supplier product page)
Size 100 ug
Price $567.80
Antigen PTPN12
Clone
Host Rabbit
Isotype IgG
Conjugate HRP
Target Species Human, Mouse, Rat
Applications ELISA, ICC, IHC-P, WB
Description Rabbit polyclonal antibody against PTPN12 conjugated to HRP -
About PTPN12 and HRP
PTPN12 The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
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HRP Excitation and Emission Spectra