PIN1 / Biotin /

Product Details
Supplier Biorbyt
Catalog #: orb356079-Biotin (View supplier product page)
Size 100 ug
Price $574.60
Antigen PIN1
Clone
Host Rabbit
Isotype IgG
Conjugate Biotin
Target Species Human
Applications ICC, IF
Description Rabbit polyclonal antibody to PIN1
About PIN1 and Biotin
PIN1 Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011]
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Biotin Excitation and Emission Spectra