Perforin / CF488A /

Product Details
Supplier Biorbyt
Catalog #: orb239658-CF488A (View supplier product page)
Size 100 ug
Price $574.60
Antigen Perforin
Clone
Host Rabbit
Isotype IgG
Conjugate CF488A
Target Species Human
Applications ICC, IF
Description Rabbit polyclonal antibody to Perforin-1
About Perforin and CF488A
Perforin This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017]
CF488A CF®488A from Biotium is a fluorophore with an excitation peak at 490 nm and an emission peak at 515 nm. It is spectrally similar to Fluorescein, Alexa Fluor™ 488 and DyLight™ 488. It can be use in fluorescence microscopy and flow cytometry. In microscopy, CF®488A has been specifically validated for STORM, STED, Structured Illumination (SIM), 2-Photon microscopy and TIRF.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

CF488A Excitation and Emission Spectra