PCDHGA4 / Unconjugated /

Product Details
Supplier Biorbyt
Catalog #: orb580708 (View supplier product page)
Size 100 ul
Price $527.00
Antigen PCDHGA4
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Animal, Bovine, Canine, Guinea Pig, Human, Mouse, Rat, Zebrafish
Applications WB
Description Rabbit polyclonal antibody to PCDHGA4 -
About PCDHGA4 and Purified
PCDHGA4 This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Purified Excitation and Emission Spectra