DCC / Biotin /

Product Details
Supplier Biorbyt
Catalog #: orb732409 (View supplier product page)
Size 100 ul
Price $598.40
Antigen DCC
Clone
Host Rabbit
Isotype IgG
Conjugate Biotin
Target Species Human, Mouse
Applications
Description Rabbit polyclonal antibody against Netrin receptor DCC conjugated to Biotin -
About DCC and Biotin
DCC This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma. [provided by RefSeq, Oct 2009]
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Biotin Excitation and Emission Spectra