NLRP2 / HRP /

Product Details
Supplier Biorbyt
Catalog #: orb468316 (View supplier product page)
Size 100 ug
Price $567.80
Antigen NLRP2
Clone
Host Rabbit
Isotype IgG
Conjugate HRP
Target Species Human, Mouse, Rat
Applications ELISA, ICC, IHC-P, WB
Description Rabbit polyclonal antibody against NALP2 conjugated to HRP -
About NLRP2 and HRP
NLRP2 This gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR). Members of this gene family are thought to be important regulators of immune responses. This gene product interacts with components of the IkB kinase (IKK) complex, and can regulate both caspase-1 and NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) activity. The pyrin domain is necessary and sufficient for suppression of NF-kB activity. An allelic variant (rs147585490) has been found that is incapable of blocking the transcriptional activity of NF-kB. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]
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HRP Excitation and Emission Spectra