MLKL / Biotin /

Product Details
Supplier Biorbyt
Catalog #: orb412360-Biotin (View supplier product page)
Size 100 ug
Price $533.80
Antigen MLKL
Clone
Host Rabbit
Isotype IgG
Conjugate Biotin
Target Species Human
Applications ICC, IF
Description Rabbit polyclonal antibody to MLKL
About MLKL and Biotin
MLKL This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2015]
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Biotin Excitation and Emission Spectra