CD160 / APC / BY55
CD160 / APC / BY55
Product Details
| Supplier | Abeomics | |
|---|---|---|
| Catalog #: | 30-1818-100-100TESTS (View supplier product page) | |
| Size | 100 Tests | |
| Price | $504.00 | |
| Antigen | CD160 | |
| Clone | BY55 | |
| Host | Mouse | |
| Isotype | IgM | |
| Conjugate | APC | |
| Target Species | Human | |
| Applications | FC, IP | |
| Description | Anti-CD160 Monoclonal Antibody (Clone:BY55)-APC Conjugated |
About CD160 and APC
| CD160 | CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |
Citations
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