IL-18 / Unconjugated / 74

Product Details
Supplier Biorbyt
Catalog #: orb304024 (View supplier product page)
Size 100 ug
Price $722.50
Antigen IL-18
Clone 74
Host Rat
Isotype IgG2a
Conjugate Unconjugated
Target Species Mouse
Applications
Description Rat monoclonal antibody to IL18 -
About IL-18 and Purified
IL-18 The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2020]
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Purified Excitation and Emission Spectra