HLA DRA / CF594 /

Product Details
Supplier Biorbyt
Catalog #: orb378103-CF594 (View supplier product page)
Size 100 ug
Price $533.80
Antigen HLA DRA
Clone
Host Rabbit
Isotype IgG
Conjugate CF594
Target Species Human, Mouse, Rat
Applications ICC, IF
Description Rabbit polyclonal antibody to HLA-DRA. -
About HLA DRA and CF594
HLA DRA HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. This molecule is expressed on the surface of various antigen presenting cells such as B lymphocytes, dendritic cells, and monocytes/macrophages, and plays a central role in the immune system and response by presenting peptides derived from extracellular proteins, in particular, pathogen-derived peptides to T cells. The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq, Aug 2020]
CF594 CF®594 from Biotium is a fluorophore with an excitation peak at 593 nm and an emission peak at 614 nm. It can be useful in both fluorescence microscopy and flow cytometry. It is spectrally similar to Alexa Fluor™ 594, DyLight™ 594 and Texas Red. However, in flow cytometry, PE-CF®594 and PE-Dazzle 594 are superior alternatives. In microscopy, CF®594 has been validated in STED and 2-Photon microscopy.
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CF594 Excitation and Emission Spectra