HAP1 / Biotin /

Product Details
Supplier Biorbyt
Catalog #: orb452626 (View supplier product page)
Size 100 ug
Price $567.80
Antigen HAP1
Clone
Host Rabbit
Isotype IgG
Conjugate Biotin
Target Species Human, Mouse, Rat
Applications ELISA, ICC, IF, IHC-P
Description Rabbit polyclonal antibody against HAP1 conjugated to Biotin -
About HAP1 and Biotin
HAP1 Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
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Biotin Excitation and Emission Spectra