GRPR / Unconjugated /

Product Details
Supplier Biorbyt
Catalog #: orb85316 (View supplier product page)
Size 50 ug
Price $725.90
Antigen GRPR
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Canine, Equine, Human, Monkey, Porcine
Applications IHC-P
Description Rabbit polyclonal antibody to GRPR
About GRPR and Purified
GRPR Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra