Glutamate Receptor 1 / CF647 /

Product Details
Supplier Biorbyt
Catalog #: orb13446-CF647 (View supplier product page)
Size 100 ug
Price $479.40
Antigen Glutamate Receptor 1
Clone
Host Rabbit
Isotype IgG
Conjugate CF647
Target Species Human, Mouse, Rat
Applications ICC, IF
Description Rabbit polyclonal to GRM1 -
About Glutamate Receptor 1 and CF647
Glutamate Receptor 1 This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
CF647 CF®647 from Biotium is a fluorophore with an excitation peak at 642 nm and an emission peak at 662 nm. It can be useful in both fluorescence microscopy and flow cytometry. It is spectrally similar to Alexa Fluor™ 647, DyLight™ 649 and Cy5.
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CF647 Excitation and Emission Spectra