NMDAR NR2A / ATTO 594 / S327A-38

Product Details
Supplier Biorbyt
Catalog #: orb150398 (View supplier product page)
Size 100 ug
Price $646.00
Antigen NMDAR NR2A
Clone S327A-38
Host Mouse
Isotype IgG2b
Conjugate ATTO 594
Target Species Human, Mouse, Rat
Applications WB, ICC, IHC
Description Mouse monoclonal antibody against GRIN2A conjugated to ATTO-594 -
About NMDAR NR2A and ATTO 594
NMDAR NR2A This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
ATTO 594 ATTO 594 from ATTO-TEC has an excitation peak at 601 nm and an emission peak at 627 nm. ATTO 594 is a novel fluorescent label belonging to the class of rhodamine dyes. Characteristic features of the label are strong absorption, high fluorescence quantum yield, high thermal and photo-stability, and excellent water solubility. Thus ATTO 594 is highly suitable for single-molecule detection applications and high-resolution microscopy such as PALM, dSTORM, STED etc. Additionally the dye highly qualifies to be applied in flow cytometry (FACS), fluorescence in-situ hybridization (FISH) and many more. ATTO 594 is very hydrophilic and shows a very good water solubility. After coupling to a substrate the label carries a net electrical charge of -1.
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ATTO 594 Excitation and Emission Spectra