CD130 / HRP /

Product Details
Supplier Biorbyt
Catalog #: orb479604 (View supplier product page)
Size 100 ug
Price $567.80
Antigen CD130
Clone
Host Rabbit
Isotype IgG
Conjugate HRP
Target Species Human, Mouse, Rat
Applications ELISA, IHC-P, WB
Description Rabbit polyclonal antibody against gp130 conjugated to HRP -
About CD130 and HRP
CD130 The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014]
Citations
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Reviews & Ratings
HRP Excitation and Emission Spectra