FPR1 / Unconjugated /

Product Details
Supplier Biorbyt
Catalog #: orb13410 (View supplier product page)
Size 100 ug
Price $365.50
Antigen FPR1
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse, Porcine, Rat
Applications ICC, IF, IHC-P, WB
Description FPR1 (Formyl Peptide Receptor 1) is a Protein Coding gene. Diseases associated with FPR1 include Susceptibility To Localized Juvenile Periodontitis and Periodontitis 1, Juvenile. Among its related pathways are Peptide ligand-binding receptors and Innate Immune System. GO annotations related to this gene include G-protein coupled receptor activity and RAGE receptor binding. An important paralog of this gene is FPR2. FPR1 High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system -
About FPR1 and Purified
FPR1 This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.[provided by RefSeq, Jul 2010]
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Purified Excitation and Emission Spectra